6. Conclusion
This review has argued about prior studies that were conducted about applying fuzzy methods in disease diagnosis. In this investigation, the main goal was to assess the effect of fuzzy methods and their frequency on improving diagnosis to decrease errors in misdiagnosis, with meta-analysis systematic review. Therefore, we designed search strategy based on our main goal. In this regard, eight scientific databases include PubMed, Google Scholar, IEEE, Science Direct, Web of Science, Taylor & Francis, Wiley Online Library, and Emerald were selected to retrieve the published scientific papers in a period of 2005 to 2017. In order to meet the goals of this study, all found papers were classified by authors, the publication year, journals or conferences type, the fuzzy methods, main objectives of the research, problems and research gaps, tools utilized to model fuzzy system, medical disciplines, sample size, the inputs and outputs of the system, findings, results and finally the impact of applied fuzzy method to improve diagnosis. Additionally, we classified our results based on their publishers and the databases with reviewing relevant articles which have been retrieved by the search strategy. The results showed that the rate of publishing articles in this domain has been increased. In this study, more favorable journals and conferences related to our issue were determined with their frequency and percentage. Another goal in this review was to determining the most utilized fuzzy methods among researchers. Returning to the question posed at the beginning of this study, it is now possible to state that the use of fuzzy logic is a beneficial way to improve the accurate diagnosis of diseases, because most of the studies declared positive impact of fuzzy methods in diagnosing various diseases. The most obvious finding to emerge from this study is that applying the fuzzy method, in addition to improve the diagnosis of diseases, can provide an early detection of the disease in order to prevent the progression of complex diseases. Another key point to remember is that we identified 13 fuzzy methods which are the most used in recent studies and we represented our results based on this classification. In addition, the impact of each fuzzy method based on the degree of effects reported by articles, was investigated. Hence, we hope that this review will serve as a base for future studies; a summary of the articles reviewed based on the impact of the applied fuzzy method along with their classification are also provided in the Appendix B in order to be used by researchers in future research.