7. Conclusion
In this work, the batch cooling crystallization procedure is investigated to develop an appropriate optimization strategy. The influence of the solubility is studied to characterize the temperature of batch cooling crystallization. Temperature control policy is necessary in the batch cooling crystallization to provide a suitable crystal size distribution for the product through the optimization. Hence, batch cooling crystallization is initially modeled. Then, objective functions are used to optimize the temperature of crystallization through a genetic algorithm. Maximum mean size, closeness to the desired value (desired mean weight size) and the minimum coefficient of variation are applied to optimize the temperature profile by the genetic algorithm. Results show that the desired value objective function that is presented in the first time is the best objective function. The mean relative error of this objective function is lower than other functions that presented in this study.