دانلود رایگان مقاله سلامت یکپارچه سطوح کمتر از حد مطلوب در تعدادی از نشانگرهای زیستی حیاتی

ABSTRACT

Background: Health checks are becoming more available in the community, with the intention of disease detection and prevention in asymptomatic people. This article summarises findings in an Australian adult sample from a health check conducted at the National Institute of Integrative Medicine (NIIM). There has been controversy regarding reference ranges and what constitutes optimal and standard reference ranges. Biomarkers were compared with standard reference ranges, and with optimal health reference ranges. Methods and results: A total of 139 participants voluntarily undertook the NIIM Health Check across a 4 year period. Participants underwent a full day of medical examinations, including liver and kidney function, thyroid, full blood count, glucose, vitamin and mineral tests. Suboptimal values were evident in a large portion of participants in vitamin D, vitamin B12, homocysteine, and iodine levels. Variables such as age, gender, body mass index (BMI) and season were important covariates. Conclusion: The sub-optimal levels in vitamin D, vitamin B12, sub-standard levels in iodine, and excessive homocysteine, were consistent with previous population studies and are associated with a number of preventable diseases such as dementia, hypertension, cancer and thyroid disease. Our analysis highlights the importance to screen for biomarkers prone to deficiencies in Australia.

5. Conclusion

Our results are in line with the literature, which indicated that Australian adults are prone to suboptimal vitamin D and vitamin B12 levels, sub-standard iodine levels and high homocysteine levels. Regular monitoring, taking into account age, gender, BMI and seasonal differences would help prevent associated problems and illnesses. Health check programmes such as the NIIM Health Check have the potential in determining significant deficiencies and health concerns by a standard suite of simple blood tests.