- مبلغ: ۸۶,۰۰۰ تومان
- مبلغ: ۹۱,۰۰۰ تومان
Among various separation techniques, the simulated moving bed (SMB) process has received special attention, especially the asynchronous SMB that allocates the columns into four zones in a flexible way. With the relative switching times as variables in the Cartesian coordinates system, all applicable switching strategies in asynchronous SMB can be visualized in a dodecahedron with the initial configuration as the origin. Thus, any point in the dodecahedron represents a switching strategy, which could be easily obtained with initial configuration and coordinates. The dodecahedron includes 14 traditional SMB configurations, represented by the 14 vertexes of the dodecahedron. Based on the dodecahedron, the optimization of the asynchronous SMB was conducted through two case studies. Compared to traditional SMB, the feed flow rates were increased by 87% in the enantioseparation of 1,1′-bi-2-naphthol and 15% in the separation of glucose and fructose without the loss of product purities.
In the present work we used a dodecahedron to describe the switching strategies of the asynchronous SMB. The relative switching times were taken as the three variables of the Cartesian coordinates and the initial configuration was regarded as the origin. The dodecahedron covers all the configurations applicable for the asynchronous SMB, including traditional SMB represented by the 14 vertexes of the dodecahedron. Every point in the dodecahedron could be easily converted to the average configuration in the switching strategies. Not only did the dodecahedron provide a visualized description of the asynchronous SMB process, but it also simplified the optimization and design of the switching strategy for the asynchronous SMB. Based on the dodecahedron, the optimization of asynchronous SMB was demonstrated in two cases. In the enantioseparation of 1,1 -bi-2-naphthol, the feed flow rate was increased by 87% with the optimized asynchronous switching strategy, withoutthe loss of product purities and additional investment. In the separation of glucose and fructose, compared to the traditional SMB, the feed flow rate under the optimized asynchronous SMB was increased by 15%.