- مبلغ: ۸۶,۰۰۰ تومان
- مبلغ: ۹۱,۰۰۰ تومان
Coronary artery heart disease (CHD) is a major cause of adult cardiovascular morbidity and mortality (1). Atherosclerosis (AS) has been shown to be a critical step in CHD, and lipid metabolism disorder is a key factor in AS (2). Recent studies have found that most CHD patients have a family history of CHD and that genetic factors play an important role in the incidence of CHD (3). However, the genetic risk factors of CHD have not been fully determined. CD36, a member of the B family of scavenger receptors, has been shown to be a high-affinity receptor for oxidized low-density lipoprotein (ox-LDL) and plays a key role in the development of AS (4). It has already been demonstrated that CD36 expression is significantly increased in CHD patients and that this could reflect the severity of coronary artery AS to a certain degree (5,6).