6. General conclusion
The main underlying theme in this review is the competitiveconflictual nature of pain, and the individual's adaptation to it, whether we look at the momentary interruptive effect, its interfering effects on the pursuit of daily life goals, or at the macro level of the sense of “self”. Clinically, this modern learning approach, incorporating cognitive, affective, behavioral and motivational aspects has made a contribution to advance our understanding of the development and reduction of persistent disability, but considerable challenges remain in order to harvest the full benefit of the knowledge gained. Future efforts should focus on developing more specific assessment procedures that could direct clinicians to the best treatment options and optimize tailoring. Although exposure techniques are clearly helpful, there is promise in developing them further incorporating our knowledge on generalization, inhibition and goal pursuit. These new avenues are likely to strengthen our treatment arsenal for individuals suffering chronic pain and disability.