دانلود رایگان مقاله انگلیسی شیوع واژینوز باکتریال و ارتباط آن با عوامل خطر در زنان غیر باردار - هینداوی 2018

Bacterial vaginosis (BV) is an ecological imbalance of the vaginal microbiota affecting mostly women of reproductive age group. This study was carried out among 160 nonpregnant women registered at the Outpatient Department of Gynaecology/Obstetrics of KIST Medical College Teaching Hospital, Imadol, Lalitpur, Nepal, from November 2014 to May 2015. The aim of the study was to assess the association of the risk factors with BV and analyze the type of bacteria associated with BV. Nugent’s scoring method was used for diagnosis of BV in this study. The overall prevalence of BV was 24.4% among symptomatic patients. Douching was statistically related to BV (? = 0.015). Also, BV was significantly associated with consistency (? = 0.0001), odor (? = 0.02), and amount of abnormal vaginal discharge (? = 0.09). Contraceptives users on anatomical sites were found more prone to BV than those who did not use contraceptives on anatomical sites. Pseudomonas spp., Escherichia coli, Acinetobacter spp., Proteus spp., Klebsiella spp., Neisseria gonorrhoeae, Enterobacter spp., Citrobacter spp., Staphylococcus aureus, Coagulase-Negative Staphylococci (CoNS), and Streptococcus agalactiae were associated with BV and out of those Lactobacillus spp. was the predominant organism. The higher prevalence of BV among symptomatic patients indicates interventions should be applied to reduce the incidence of stillbirth, abortion, and sterility.

5. Conclusion

The study suggests that using contraceptives on anatomical sites may confer a higher risk for BV. Some factors, especially vaginal douching, may increase the risk of BV. Lactobacillus spp. were the predominant isolates found in the vaginal sample followed by a number of Enterobacteriaceae members and Gram positive bacteria. This finding suggests that the colonization of facultative anaerobes is also more likely a consequence in vaginal ecology. Limited studies on BV have been performed in Nepal. So, similar studies must be carried out in order to improve the health status of women, thereby preventing the risk posed towards BV.