دانلود رایگان مقاله انگلیسی پذیرفتن بیماران مبتلا به تشنج ناشی از تب برای مدیریت بیشتر - الزویر 2017

ABSTRACT:

Background and aims: Children with first complex febrile seizure (CFS) are often admitted for observation. The goals of this study were 1) to assess the risk of seizure recurrence during admission, 2) to determine whether early EEG affects acute management. Design/Methods: We retrospectively reviewed a cohort of children 6-60 months of age admitted from a Pediatric Emergency Department for first CFS over a 15 year period. We excluded children admitted for supportive care of their febrile illness. Data extraction included age, gender, seizure features, laboratory and imaging studies, EEG, further seizures during admission, and antiepileptic drugs (AEDs) given. Results: One hundred eighty three children met inclusion criteria. Seven patients had seizures during the admission (7/183 or 3.8%) Since 38 children were loaded with anti-epileptic medication during their visit, the adjusted rate is 7/145 or 4.8 Increased risk of seizure recurrence during admission was observed in children presenting with multiple seizures (P=0.005). EEG was performed in 104/183 children (57%) and led to change in management in one patient (1%, 95% C.I. 0.05- 6%). Six of the 7 children with seizure had an EEG. The study was normal in 3 and findings in the other 2 did not suggest/predict further seizures during the admission. Conclusions: Children with first CFSs are at low risk for seizure recurrence during admission. Multiple seizures at presentation are associated with risk of early recurrence and may warrant an admission. EEG had limited effect on acute management and should not be an indication for admission.

CONCLUSIONS

Patients admitted for observation after CFS have a low rate of seizure recurrence, though patients with multiple seizures as the presenting feature are at higher risk for seizure recurrence. EEG findings had limited effect on acute management and should not be a sole reason for admission of these children.