ABSTRACT

Based on the future drug delivery vehicle,a drug in nanoformulation based on targeted drug delivery for effective treatment of cancer is developed. The drug is a Nano formulation consisting of a Nanocarrier, Cancer specific receptor or general receptor, Sensing material to identify if the cell is normal, malignant or benign, Substance to indicate the amount of uptake of the nanomaterial by the cell for the staging of cancer, a drug wrapped in a charged molecule, stabilizing and binding agent.When an external electrical potential is applied to the solution containing the mixture of stabilizing or binding agent, drug, cancer specific receptor or general receptor, sensing material, the binding agent loses its negative charge, which causes the nanoformulation to disintegrate, releasing the drugs. The amount of drug delivered and the timing of the dose can be precisely controlled by turning the voltage on and off. The electrical signal can be remotely administered (for example, by a physician) using radio signals or other techniques that have already been developed for other biomedical devices. The formulation can carry discrete packets of drugs that can be released separately, which could be especially beneficial for chemotherapy.