Bioactive components found in seaweed is very prospective to be applied in cosmetics. One type of seaweed with unknown characteristics is Caulerpa sp. This study aimed to determine the content Caulerpa which can be a component of raw material for making cosmetic. The analysis were for the proximate with AOAC method, amino acids, vitamins A, B and E using by HPLC, phytochemical test method Harborne, antioxidant activity (DPPH) and total phenols (Folin-Ciocalteau). Proximate Caulerpa sp. showed that consecutive include water 76.065%, 1.231% ash, 3.73% protein, 0.35% fat, and carbohydrates 18.645%. The dominant amino acids resulted was glutamate, histidine, arginine, aspartate, tyrosine, alanine, and valine [greater of 100 mg · (100 g)–1]. 487.09 mg · (100 g)–1 Vitamin A, Vitamin B 0.42 mg · (100 g)–1, Vitamin E 2.22 mg · (100 g)–1. Derived bioactive components consis of steroids, flavonoids, phenols hydroquinone and saponin, with total phenol at 0.0441 mg GAE · g–1 and antioxidant activity with IC50 of 451.27 mg · kg–1.
