دانلود رایگان مقاله انگلیسی ارتباط بین ارائه محیطی آفت کش ها و صرع - الزویر 2018

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عنوان فارسی

ارتباط بین ارائه محیطی آفت کش ها و صرع

عنوان انگلیسی

Association between environmental exposure to pesticides and epilepsy

صفحات مقاله فارسی

صفحات مقاله انگلیسی

سال انتشار

2018

نشریه

الزویر - Elsevier

فرمت مقاله انگلیسی

PDF

نوع مقاله

ISI

نوع نگارش

مقالات پژوهشی (تحقیقاتی)

رفرنس

دارد

پایگاه

اسکوپوس

کد محصول

E9499

رشته های مرتبط با این مقاله

پزشکی

گرایش های مرتبط با این مقاله

مغز و اعصاب

مجله

سم شناسی عصبی - NeuroToxicology

دانشگاه

University of Almería School of Health Sciences - Almería - Spain

کلمات کلیدی

آفت کش ها؛ تماس با محیط زیست؛ صرع

doi یا شناسه دیجیتال

https://doi.org/10.1016/j.neuro.2018.07.002

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چکیده

Abstract

There is increasing evidence of an association between long-term environmental exposure to pesticides and neurodegenerative disorders; however, the relationship with epilepsy has not been addressed thus far. This study was aimed at determining the prevalence and risk of developing epilepsy among people from South-East Spain living in areas of high vs. low exposure to pesticides based on agronomic data. The study population consisted of 4007 subjects with a diagnosis of epilepsy and 580,077 control subjects adjusted for age, sex and geographical area. Data were collected from hospital records of the Spanish health care system (basic minimum dataset) between the years 1998 and 2010. The prevalence of epilepsy was significantly higher in areas of greater pesticide use relative to areas of lesser use. Overall, an increased risk of epilepsy was observed in the population living in areas of high vs. low use of pesticides (OR:1.65; p <0.001). Although this study was exploratory in nature, the results suggest that environmental exposure to pesticides might increase the risk of having epilepsy.

نتیجه گیری

5. CONCLUSION

While numerous studies have shown an association between acute pesticide exposure and further development of seizures, no study addressed the relationship between long-term low-dose exposure to pesticides and epilepsy. This study indicates that hospital-diagnosed epilepsy prevalence was higher in those health districts where a higher pesticide use was made in intensive agriculture under plastic greenhouses. However, the limitations inherent to the study design warrant further research to ascertain whether there exists a true causal association.

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