دانلود رایگان مقاله انگلیسی پاتولوژی تاندون در بیماران مبتلا به هیپوکلسترولمی: اپیدمیولوژی، پاتوژنز و مدیریت - الزویر 2018

عنوان فارسی
پاتولوژی تاندون در بیماران مبتلا به هیپوکلسترولمی: اپیدمیولوژی، پاتوژنز و مدیریت
عنوان انگلیسی
Tendon pathology in hypercholesterolaemia patients: Epidemiology, pathogenesis and management
صفحات مقاله فارسی
0
صفحات مقاله انگلیسی
9
سال انتشار
2018
نشریه
الزویر - Elsevier
فرمت مقاله انگلیسی
PDF
نوع مقاله
ISI
نوع نگارش
مقالات مروری
رفرنس
دارد
پایگاه
اسکوپوس
کد محصول
E9580
رشته های مرتبط با این مقاله
پزشکی
گرایش های مرتبط با این مقاله
پاتولوژی، اپیدمیولوژی
مجله
مجله ارتوپدی - Journal of Orthopaedic Translation
دانشگاه
Department of Cardiovascular Disease - The Second Xiangya Hospital - Central South University - PR China
کلمات کلیدی
همه گیرشناسی؛ هیپرکلسترولمی؛ مدیریت؛ پاتوژنز؛ آسیب شناسی تاندون
doi یا شناسه دیجیتال
https://doi.org/10.1016/j.jot.2018.07.003
چکیده

Abstract


Tendon pathology is a general term used to describe a group of musculoskeletal conditions related to tendons and surrounding structures. There is only limited evidence available regarding the exact aetiology and natural history of tendon pathology. In hypercholesterolaemia environments, lipids could accumulate within the extracellular matrix of the tendon and thus affect the mechanical properties of the tendon. Current evidence suggested that hypercholesterolaemia was an important risk factor in the development and progression of tendon pathology. The severity of hypercholesterolaemia was correlated with the severity of tendon pathology. The translational potential of this article: Hypercholesterolaemia lead to the structural, inflammatory and mechanical changes in tendons, which predispose hypercholesterolaemia patients to a greater risk of tendon pathology. Measurements of serum cholesterol are suggested to be performed in patients presenting with tendon pathology. The strict control of hypercholesterolaemia would mitigate the development and progression of tendon pathology.

نتیجه گیری

Conclusion


Current evidence generally suggested that hypercholesterolaemia was an important risk factor in the development and progression of tendon pathology. The severity of hypercholesterolaemia was correlated with the severity of tendon pathology. Hypercholesterolaemia lead to the structural, inflammatory and mechanical changes in tendons, which predispose hypercholesterolaemia patients to a greater risk of tendon pathology. The strict control of hypercholesterolaemia would mitigate the development and progression of tendon pathology.


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