دانلود رایگان مقاله متاستاز آدنوکارسینوما رکتوم حلقه به پستان در زن جوان

abstract

Breast metastasis of malignant tumors is very rare. The most common malignant tumor in this organ is of primary ductal origin. The most common site of metastasis in colorectal adenocarcinoma is liver. Metastasis of colorectal cancer to the breast parenchyma is an extremely rare event. Since 25 years ago, 22 cases of colorectal metastasis to the breast, presenting as breast mass have been reported in the English literature. In this case report, we will describe our experience with a young lady presenting with a breast mass 10 years after the diagnosis of colorectal cancer. Less than a year after excision of the breast mass (lumpectomy), the breast metastasis became so extensive that palliative mastectomy was the only palliative surgery to be performed for her. To the best of our knowledge our patient is the youngest case of breast metastasis from colorectal adenocarcinoma developing 10 years after surgery (the longest interval reported so far). Keywords

3. Discussion

Signet ring carcinoma of the breast, has previously been de- fined as a subtype of mucin producing carcinomas, however it's no longer considered by the World Health Organization (WHO) to represent a distinct entity [3,4] Presence of signet ring adenocarcinoma in the breast can be seen in two broad categories of tumors i.e. primary and metastatic carcinoma, so in every signet ring adenocarcinoma of the breast primary breast signet ring adenocarcinoma should be considered as the first diagnosis, because signet ring cells can be seen in different histological types of invasive breast carcinoma (ductal, lobular, metaplastic and mucinous) [3–5]. On the other hand, breast metastasis from extra mammary sites is rare and less than 400 cases have been reported during the last 25 years in the English literature and overall metastatic tumors of the breast consist of only 2.7% of all breast tumors [2]. Metastasis of gastrointestinal tumors including colon to the breast is even more uncommon and to the best of our knowledge 22 cases of metastatic breast tumors from the colon have been reported during the last 25 years, in the English literature [3].