ترجمه مقاله نقش ضروری ارتباطات 6G با چشم انداز صنعت 4.0
- مبلغ: ۸۶,۰۰۰ تومان
ترجمه مقاله پایداری توسعه شهری، تعدیل ساختار صنعتی و کارایی کاربری زمین
- مبلغ: ۹۱,۰۰۰ تومان
Medical advances in neonatology have significantly improved survival statistics, particularly for extremely preterm infants. Similar progress has not been made to improve neurodevelopmental outcomes for brain-injured neonates. Clinical trials of hypothermia have demonstrated benefit for term neonates with mild and moderate brain injury, but none when hypoxia-ischemia is severe or prolonged [1,2,3]. Hypothermia is also contraindicated for preterm infants, leaving this group with no proven therapeutic options when hypoxia-ischemia occurs. A neuroprotective pharmaceutical treatment to minimize neonatal brain injury is greatly needed. The optimal therapy will be safe for use in both preterm and term neonates, and effective when administered after an insult. Animal studies support the efficacy and safety of erythropoietin (Epo) as a therapeutic intervention for a variety of brain insults [4*], and Epo is now in the clinical testing phase. We highlight recent clinical trials and experimental reports that further consideration of Epo as a therapy for neonatal hypoxic-ischemic injury.