- مبلغ: ۸۶,۰۰۰ تومان
- مبلغ: ۹۱,۰۰۰ تومان
High-density biomolecule arrays are powerful tools for the screening of pharmaceuticals, investigation of biomolecule interactions and patient diagnostics. Surfaces modified with electrochemically addressable films combined with electrochemical surface patterning techniques allow local triggering of DNA and protein immobilization. After a brief overview of classical patterning methods, such as printing, dippen nanolithography (DPN) and photolithography, we critically assess electrochemical strategies for local surface modification, such as the use of electrode arrays, electro-DPN and scanning electrochemical microscopy regarding their potential for fabrication and read-out of bioarrays. Capillary-based scanning probe methods are especially promising tools for truly chemoselective microarray and nanoarray generation due to their high patterning resolution and the possibility for directly probing the surface chemistry.