ترجمه مقاله نقش ضروری ارتباطات 6G با چشم انداز صنعت 4.0
- مبلغ: ۸۶,۰۰۰ تومان
ترجمه مقاله پایداری توسعه شهری، تعدیل ساختار صنعتی و کارایی کاربری زمین
- مبلغ: ۹۱,۰۰۰ تومان
associated with various complications such as diabetic nephropathy. It is most common cause of End Stage Renal Disease (ESRD) in diabetic individual. In various studies, altered levels of serum copper levels are associated with diabetic complications such as diabetic nephropathy. We studied serum copper levels in type 2 diabetic individual with and without nephropathy.
Materials and Methods- The study population consisted of 100 type 2 diabetic individual which was further divided into two groups, first group consisted of 50 diabetic individual with nephropathy and second group consisted of 50 diabetic individual without nephropathy. Diabetic nephropathy status was assessed by spot urinary albumin creatinine ratio and GFR. Serum copper levels were measured by colorimetric method.
Result- Mean serum copper levels were significantly higher in diabetic patient with nephropathy (111.8 ± 13.9 mg/dl) as compare to diabetic patient without nephropathy (102.3 ± 16.2 mg/dl), (p = 0.002). Serum copper was also positively correlated with weight of subject (r = 0.263, p = 0.009), and negatively correlate with serum zinc (r = -0.263, p = 0.009).
Conclusion- Diabetic nephropathy is the leading cause of death in diabetic individual. Our study points toward the increased serum copper levels are associated with diabetic nephropathy. Thus we could use copper chelator in an attempt to decrease serum copper, so that diabetic nephropathy could be prevented and thus improve overall management of diabetic individual.