دانلود رایگان مقاله غده سباسه در خارج از مری

Summary

Ectopic sebaceous glands (ESGs) are benign esophageal lesions that have a lower detection rate than malignant lesions because most patients are asymptomatic. However, this rate can be increased by the widespread use of endoscopes and an increasing awareness of the disease. Through esophagogastroduodenoscopy, ESGs often appear in the middle and lower esophagus in numbers ranging from 1 to more than 100 yellowish plaques measuring 1 e2 mm in diameter. Histopathological examination of ESGs would reveal small lobular cluster glands in the lamina propria. Diagnosis is usually confirmed through an endoscopic biopsy. ESGs are best distinguished from other yellowish lesions such as xanthoma via endoscopy. These lesions tend to appear singly scattered, whereas xanthomas tend to be clustered. We present three cases of ESGs in the esophagus. Although their etiologies are still unclear, we present related theories in our review.

Discussion

ESGs and xanthomas in the esophagus (Figure 5) have similar epidemiology, such as patient age (mean, 50 years), endoscopic features (yellowish, small, mildly elevated lesions), and clinical symptoms (asymptomatic), with good prognoses. To the best of our knowledge, no case reports have discussed their differences. We present three cases of ESGs and one case of xanthoma in the esophagus that had similar endoscopic findings and age distributions. A comparison between the esophageal ESGs and xanthoma is provided in Table 1. ESGs and xanthomas are rarely found in the esophagus. For ESGs in the esophagus, the typical mean patient age at onset is 50 years, with almost equal distribution in men and women [5]. For esophageal xanthoma, also known as “xanthelasma” and “lipid island,” the mean patient age at onset is 54 years, with mild predominance in men [6,7].