دانلود رایگان مقاله انگلیسی ارتباط بین کمبود ویتامین D و افسردگی در جمعیت نپال - الزویر 2018

عنوان فارسی
ارتباط بین کمبود ویتامین D و افسردگی در جمعیت نپال
عنوان انگلیسی
Association between vitamin D deficiency and depression in Nepalese population
صفحات مقاله فارسی
0
صفحات مقاله انگلیسی
19
سال انتشار
2018
نشریه
الزویر - Elsevier
فرمت مقاله انگلیسی
PDF
نوع مقاله
ISI
نوع نگارش
مقالات پژوهشی (تحقیقاتی)
رفرنس
دارد
پایگاه
اسکوپوس
کد محصول
E10076
رشته های مرتبط با این مقاله
روانشناسی، پزشکی
گرایش های مرتبط با این مقاله
روانشناسی بالینی، روانپزشکی
مجله
تحقیقات روانپزشکی - Psychiatry Research
دانشگاه
Department of Biochemistry - B.P. Koirala Institute of Health Sciences - Dharan - Nepal
کلمات کلیدی
مقیاس میزان افسردگی Beck، نپال، افسردگی، کمبود ویتامین D
doi یا شناسه دیجیتال
https://doi.org/10.1016/j.psychres.2018.06.018
چکیده

Abstract


Recent studies link vitamin D deficiency with depression; however evidences from the Nepalese population are scarce. The current study explored the association between vitamin D deficiency and depression among 300 adults of 18 years and above age residing in eastern Nepal. Validated Nepali version of the Beck Depression Inventory scale (BDI-Ia) was used to determine depressive symptoms and a BDI cutoff score of ≥ 20 was considered as clinically significant depression. Sociodemographic data were collected using semi-structured questionnaire. Blood samples were collected to measure serum 25-hydroxy vitamin D (25(OH)D) and classify vitamin D status (deficient, insufficient and sufficient). We used Chi-square test to identify the association of sociodemographic variables and vitamin D status with clinically significant depression. We found a significant association of gender, geographical location of residence, marital status, religion and vitamin D status with clinically significant depression. Binary logistic regression model was used to examine the likelihood of clinically significant depression among vitamin D deficient individuals. Vitamin D deficiency was significantly associated with increased odds of clinically significant depression even after adjusting for confounding variables. This finding suggests Vitamin D deficient people have increased odds of having clinically significant depression.

نتیجه گیری

Conclusion


Vitamin D deficiency is associated with increased odds of having depression. In a country like Nepal where cultural beliefs are deeply rooted and have profound influence in lifestyle choices, one has to go beyond merely correcting serum vitamin D level to impede depression. This study warrants a need for clinical trial to assess if supplementing vitamin D improves depression symptoms.


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