دانلود رایگان مقاله تغییرات حاد در سفتی شریان پیرو ورزش در افراد سالم

Abstract

Background: Arterial stiffness and exercise capacity are independent predictors of cardiovascular diseases. This study aims to establish the acute changes in arterial stiffness using applanation tonometry following sub-maximal exercise in Caucasians and South Asians. This study also aims to establish the relationship between exercise capacity and arterial stiffness. Methods: In total, 69 participants including 37 Caucasians and 32 South Asians were assessed for arterial stiffness non-invasively using SpygmoCor (SCOR-PVx, Version 8.0, AtCor Medical Inc North America, USA) before and after an exercise test using the Bruce protocol on a treadmill and by measuring aerobic capacity using a metabolic analyser (Medical Graphics, Cardio Control, Minnesota, USA). Results: Significant increases in arterial stiffness variables were observed including augmentation pressure, subendocardial viability ratio, ejection duration, pulse pressure, augmentation index and mean arterial pressure following exercise in both ethnic groups (P < 0.05). There were no significant differences in these increases between the ethnic groups (p > 0.05). There was no change in pulse wave velocity (p > 0.05). Exercise capacity was inversely related to arterial stiffness (P < 0.05). Conclusion: There are no differences in arterial stiffness at the baseline and following acute exercise between Caucasians and South Asians. There was significant increase in arterial stiffness following exercise in both groups. Exercise capacity is inversely related to arterial stiffness. The results suggest that non invasive arterial stiffness could be used as a tool to measure acute changes following exercise.

Conclusions

There are no differences in arterial stiffness variables at rest between Caucasians and South Asians. There was significant increase in central aortic pressures and reduction in augmentation index within 5e10 min following acute exercise in both groups. However, there was no difference in these increases due to ethnicity, gender or age. There were differences between these ethnic groups in exercise capacity and gas exchange variables during sub-maximal exercise. This may be due to a difference in adhering to a healthy lifestyle and needs to be investigated. There were strong inverse correlations between exercise capacity and arterial stiffness. Non-invasive carotid-radial arterial stiffness measurements could be used in exercise-based interventional studies. The findings of this study advance the understanding of the clinical evaluation in difference ethnic groups who are in higher risk. More studies need to be carried out on clinical populations with cardiovascular risks to enable appropriate preventive measures. Larger scale studies need to establish the validity of the individual variables of arterial stiffness using applanation tonometry