دانلود رایگان مقاله انگلیسی شیوع آنتی ژن اریتروسیت 1 سگ در 7414 سگ در ایتالیا - هینداوی 2017

The study aim was to establish the prevalence of DEA 1, the most immunogenic and clinically important blood group in canine blood transfusion, in 7,414 dogs from Italy. The potential sensitization risk following a first transfusion and the acute reaction risk following a second transfusion given without a cross-matching and blood typing test were also calculated. Dogs tested were purebred (4,798) and mongrel (2,616); 38.8% were DEA 1 negative and 61.2% were DEA 1 positive. High prevalence for DEA 1 positive blood type was found in Ariegeois and English Setter, whereas German Shepherd and Boxer had higher DEA 1 negative blood type. Breeds with blood type never reported before included French Brittany Spaniel and Pug showing a high prevalence of DEA 1 positive type, while French Bulldog and West Highland White Terrier were more often DEA 1 negative. Just 48.8% of purebred and 13.9% of mongrel dogs were considered as prospective blood donors based upon their blood type. Most of the breeds had a sensitization risk of 20.0–25.0%. Rottweiler and Ariegeois had less risk of sensitization (9.4 and 4.2%) and the minor risk of an acute transfusional reaction (0.9–0.2%). The prevalence of DEA 1 positive and negative dogs in Italy agrees with most of the data already reported in the literature.

5. Conclusions

This study provides an overview about the distribution of DEA 1 blood group in a large dog population belonging to purebred and mongrel dogs reared in Italy. The data could be useful in clinical transfusion medicine and for studies of canine genetic epidemiology. The prevalence of DEA 1 positive and negative dogs mostly agrees with previous prevalence studies reported in the literature. In addition, DEA 1 distribution was studied in breeds never previously reported. The risk of sensitization following the first transfusion and the risk of an acute transfusional reaction documented as hemolysis and/or agglutination following the second transfusion in the absence of a pretransfusional cross-match and blood typing test also was determined in most of the breeds studied.