دانلود رایگان مقاله توانایی تخریبی قارچ های کوپروفیلیک آسکومیست آنسرینا پودوسپورا

Abstract

The degradation of plant biomass is a major challenge towards the production of bio-based compounds and materials. As key lignocellulolytic enzyme producers, filamentous fungi represent a promising reservoir to tackle this challenge. Among them, the coprophilous ascomycete Podospora anserina has been used as a model organism to study various biological mechanisms because its genetics are well understood and controlled. In 2008, the sequencing of its genome revealed a great diversity of enzymes targeting plant carbohydrates and lignin. Since then, a large array of lignocellulose-acting enzymes has been characterized and genetic analyses have enabled the understanding of P. anserina metabolism and development on plant biomass. Overall, these research efforts shed light on P. anserina strategy to unlock recalcitrant lignocellulose deconstruction.

4. Conclusions and future

trends P. anserina is an ideal candidate to better understand the breakdown of plant biomass by fungi. In the last few years, studies have shed light on P. anserina enzymatic machinery to process recalcitrant lignocellulose and confirmed its potential as a source of new efficient biocatalysts. Fundamental knowledge has been acquired on the mechanisms and substrate specificities of several glycoside hydrolases, carbohydrate esterases and lytic polysaccharide monooxygenase families. Additional genetic experiments have enabled to better understand how P. anserina grows and develops on complex biomass. In the future, the combination of genetic and microbial engineering tools available for P. anserina should enable the development of synthetic biology approaches to extend its potential for white-biotechnological applications.