دانلود رایگان مقاله دوستاکسل ماکولوپاتی

عنوان فارسی
دوستاکسل ماکولوپاتی
عنوان انگلیسی
Docetaxel maculopathy
صفحات مقاله فارسی
0
صفحات مقاله انگلیسی
4
سال انتشار
2016
نشریه
الزویر - Elsevier
فرمت مقاله انگلیسی
PDF
کد محصول
E2653
رشته های مرتبط با این مقاله
پزشکی
گرایش های مرتبط با این مقاله
چشم پزشکی، آسیب شناسی، ایمنی شناسی
مجله
ارتباطات درمان سرطان - Cancer Treatment Communications
دانشگاه
وزارت چشم پزشکی، بریتانیا
کلمات کلیدی
تاکسوتر، دوستاکسل، سرطان پستان
چکیده

abstract


A 56 year old retired theatre nurse who has metastatic breast carcinoma complains of reduced vision in the left eye since being started on Docetaxel (Taxotere), an oral anti-mitotic chemotherapeutic agent. Best corrected visual acuity was 6/18 in the left eye, and 6/9-1 in the right. Clinical examination and subsequent examination with optical coherence tomography and Intravenous Fluorescein angiography revealed evidence suggestive of drug related maculopathy. No abnormal findings were present in the right eye. As far as we are aware, this is the first reported case of maculopathy following commencement of Docetaxel with the absence of macular oedema.

نتیجه گیری

4. Conclusion


As far as we are aware, this is the first reported case of maculopathy following commencement of Docetaxel (Taxotere) with a non-cystoid presentation. We advise that any patient started on Docetaxel therapy should be counselled for possible drug associated toxic maculopathy, and that this should be considered in all patients complaining of visual disturbance. The Oncologist must weigh the nature of the visual pathology and liaise the Ophthalmologist when managing such patients.


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