Abstract
Fine needle aspiration cytology continues to be the first line modality for definitive diagnosis of palpable and non palpable breast masses. Despite its high accuracy, some cases may pose a diagnostic dilemma. We present a case of a 42 year old female who was clinico-radiologically and cytologically mislabelled as plasmacytoma but was subsequently diagnosed as poorly differentiated carcinoma breast on histopathology and immunohistochemistry. Aspiration cytology is a minimally invasive procedure with rapid turn around time but in cases with unusual cytological picture, a core biopsy along with immunohistochemistry must accompany cytology to maximize the preoperative diagnosis of malignant breast lesions in order to ensure appropriate management.