دانلود رایگان مقاله انگلیسی استروئیدهای تولید مثل و علائم ADHD در دوران قاعدگی - الزویر 2018

عنوان فارسی
استروئیدهای تولید مثل و علائم ADHD در دوران قاعدگی
عنوان انگلیسی
Reproductive Steroids and ADHD Symptoms Across the Menstrual Cycle
صفحات مقاله فارسی
0
صفحات مقاله انگلیسی
29
سال انتشار
2018
نشریه
الزویر - Elsevier
فرمت مقاله انگلیسی
PDF
نوع مقاله
ISI
نوع نگارش
مقالات پژوهشی (تحقیقاتی)
رفرنس
دارد
پایگاه
اسکوپوس
کد محصول
E9776
رشته های مرتبط با این مقاله
روانشناسی، پزشکی
گرایش های مرتبط با این مقاله
روانشناسی بالینی، زنان و زایمان
مجله
Psychoneuroendocrinology
دانشگاه
Department of Psychology - University of Kentucky - Lexington - United States
کلمات کلیدی
هورمون های استروئیدی تولید مثل؛ استرادیول؛ پروژسترون؛ تستوسترون؛ ADHD
doi یا شناسه دیجیتال
https://doi.org/10.1016/j.psyneuen.2017.11.015
چکیده

Abstract


Although Attention-Deficit/Hyperactivity Disorder shows (ADHD) male predominance, females are significantly impaired and exhibit additional comorbid disorders during adolescence. However, no empirical work has examined the influence of cyclical fluctuating steroids on ADHD symptoms in women. The present study examined estradiol (E2), progesterone (P4), and testosterone (T) associations with ADHD symptoms across the menstrual cycle in regularlycycling young women (N=32), examining trait impulsivity as a moderator. Women completed a baseline measure of trait impulsivity, provided saliva samples each morning, and completed an ADHD symptom checklist every evening for 35 days. Results indicated decreased levels of E2 in the context of increased levels of either P4 or T was associated with higher ADHD symptoms on the following day, particularly for those with high trait impulsivity. Phase analyses suggested both an early follicular and early luteal, or post-ovulatory, increase in ADHD symptoms. Therefore, ADHD symptoms may change across the menstrual cycle in response to endogenous steroid changes.

نتیجه گیری

5. Conclusions


Results demonstrating steroid effects across the menstrual cycle on ADHD symptoms for vulnerable women suggests the possibility that ADHD symptoms may be more state-like and variable within women than previously thought. If results that ADHD symptoms vary across the menstrual cycle in tandem with steroid changes are replicated, this may suggest the need for clinicians to ask for information about cycle phase, hormonal profiles, use of hormonal birth control, and/or stage of life (i.e., pre- or post-puberty) during ADHD assessment in women. These results also suggest the possibility that EF and psychostimulant response might vary across the cycle. These represent critical directions for future work.


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